Factory source Anti-Cancer Paclitaxel - USP EP BP Medicine Grade 148408-66-6 Docetaxel trihydrate for Treatment of Tumor Cancer – Yibai

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Factory source Anti-Cancer Paclitaxel - USP EP BP Medicine Grade 148408-66-6 Docetaxel trihydrate for Treatment of Tumor Cancer – Yibai Detail:

Product name	Docetaxel Trihydrate
Synonyms	(αR,βS)-β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-benzenepropanoic acid, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,hydrate (1:3)
CAS No.	148408-66-6
Appearance	White to off-white crystalline powder
Molecular Formula	C₄₃H₅₃NO₁₄.3(H₂O)
Molecular Weight	861.94
Application	Pharma grade or research purpose
Packing	As per your request
Storage	Preserve in tight,light-resistant containers in a cool place

Docetaxel Trihydrate CAS# 148408-66-6
ITEMS	STANDARDS	RESULTS
Characters	A:White to off-white crystalline powder	Conforms
Characters	B:Solubility :Insoluble in water ,soluble in ethanol and acetone	Conforms
Specific Rotation	﹣38.5°～﹣41.5°	﹣40°
Identification	1.IR: The same to check sample	Conforms
	2.UV: λmax232nm	Conforms
	Colour reactions: positive reactions	Conforms
	HPLC: retention times is same as the standard sample	Conforms
Impurities	Total impurities: NMT 1.0%	0.29%
	Impurities A: NMT 0.5%	0.0551%
	Impurities B: NMT 0.3%	0.0470%
	Impurities C: NMT 0.3%	0.0535%
	Any other single impurity: NMT 0.1%	0.0702%
Water	5.0% – 7.0%	6.15%
Residue on ignition	NMT 0.1% w/w	0.03%
Heavy metal	NMT 20ppm	Conforms
Assay	97.5%~ 102.0%	99.7%
Conclusion	It meets EP7.5.

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